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Anti-SIK3 Antibody Polyclonal
Also for SIK3 (NM_025164)
|SIK3 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human SIK3.|
|Human, Mouse, Rat
||ELISA, WB: 1 ug/ml, IF: 20 ug/ml
|SIK3 Antibody is supplied in PBS containing 0.02% sodium azide.|
|SIK3 Antibody is affinity chromatography purified via peptide column.
|Homo sapiens SIK family kinase 3 (SIK3), transcript variant 1|
|L19; QSK; SIK-3|
|SIK3 Antibody: Salt-inducible kinase family (SIKs) proteins are thought to have a role in steroidogenesis, adipogenesis or regulation of tumor malignancy. Three members (SIK1, SIK2 and SIK3) in the SIK family have been identified thus far. Their kinase domain sequences are closely homologous to those of AMP-activated protein kinase (AMPK). SIK3 can be phosphorylated by a tumor-suppressor kinase LKB1. It is highly and preferentially expressed in ovarian tumors but not in adenomyosis and leiomyoma and may be a potential diagnostic marker for ovarian cancers. |
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Western blot analysis of SIK3 in rat brain tissue lysate with SIK3 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
Immunofluorescence of SIK3 in rat brain cells with SIK3 antibody at 20 ug/mL.