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Home Antibody All anti-SHPK antibodies

Anti-SHPK TRUEMAB Antibody clone 1D2

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA503209
  • SHPK (CARKL) mouse monoclonal antibody, clone 1D2
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC415695) , 20ug
100ul 325 In Stock
CF503209
  • Carrier-free (BSA/glycerol-free) SHPK mouse monoclonal antibody,clone 1D2
100ug $450 3-4 weeks
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WB(2)
IF(1)

OriGene Data

ImmunogenFull length human recombinant protein of human SHPK(NP_037408) produced in HEK293T cell.
Clone Nameclone 1D2 IsotypeIgG2a
Species ReactivityHuman Concentration0.63 mg/ml
Guaranteed Application *WB, IF Suggested Dilutions WB 1:500~2000, IF 1:100,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens sedoheptulokinase (SHPK)
Alternative NameCARKL; SHK
Database LinkNP_037408
FunctionThe protein encoded by this gene has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibiting return across the cell membrane. Sequence variation between this novel gene and known carbohydrate kinases suggests the possibility of a different substrate, cofactor or changes in kinetic properties distinguishing it from other carbohydrate kinases. The gene resides in a region commonly deleted in cystinosis patients, suggesting a role as a modifier for the cystinosis phenotype. The genomic region is also rich in Alu repetitive sequences, frequently involved in chromosomal rearrangements. [provided by RefSeq, Jul 2008].
Related Pathway

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WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SHPK (RC204421, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SHPK.
WB Image
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-SHPK monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).
IF Image
Anti-SHPK mouse monoclonal antibody (TA503209) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SHPK(RC204421).

 

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