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Anti-SHC1 PHOSPHO Antibody


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SKU Description Amount Price Availability*  
TA312072 Rabbit polyclonal Shc (Tyr427) antibody(Phospho-specific) 100ul 325
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OriGene Data

ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human Shc around the phosphorylation site of tyrosine 427 (P-S-YP-V-N).
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:500~1000, IHC: 1:50~100, ELISA: 1:10000
BufferPhosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Note Shc (phospho-Tyr427) antibody detects endogenous levels of Shc only when phosphorylated at serine 24.

Reference Data

Target NameHomo sapiens SHC (Src homology 2 domain containing) transforming protein 1 (SHC1), transcript variant 1
Alternative NameSHC; SHCA
Database LinkNP_892113
Entrez Gene 6464 Human
Related PathwayDruggable Genome ErbB signaling pathwayChemokine signaling pathwayFocal adhesionNatural killer cell mediated cytotoxicityNeurotrophin signaling pathwayInsulin signaling pathwayMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of extracts from Hela cells treated with Calyculin A (50ng/ml, 15mins), using Shc (phospho-Tyr427) antibody.The lane on the right is treated with the synthesized peptide.
Immunohistochemical analysis of paraffin-embedded human brain tissue using Shc (phospho-Tyr427) antibodyThe picture on the right is treated with the synthesized peptide.


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