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Home Antibody All anti-SH2B3 antibodies

Anti-SH2B3 TRUEMAB Antibody clone 1E6

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA502762
  • SH2B3 (LNK) mouse monoclonal antibody, clone 1E6
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401678) , 20ug Explanation
100ul $325 In Stock
CF502762
  • Carrier-free (BSA/glycerol-free) SH2B3 mouse monoclonal antibody, clone 1E6
100ug $450 3-4 weeks
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WB(1)
IF(1)
FC(1)
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Also for SH2B3 (NM_005475)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human SH2B3 (NP_005466) produced in HEK293T cell.
Clone Nameclone 1E6 IsotypeIgG1
Species ReactivityHuman Concentration0.6 mg/ml
Guaranteed Application *WB, IF, FC Suggested DilutionsWB 1:2000, IF 1:100, FLOW 1:100
Predicted MW Explanation 63 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens SH2B adaptor protein 3 (SH2B3), transcript variant 1
Alternative NameIDDM20; LNK
Database LinkNP_005466
Entrez Gene 10019 Human
FunctionThis gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin-dependent diabetes mellitus.
Related Pathway Neurotrophin signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SH2B3 (RC218359, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SH2B3.
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Anti-SH2B3 mouse monoclonal antibody (TA502762) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SH2B3(RC218359 ).
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HEK293T cells transfected with either RC218359 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-SH2B3 antibody(TA502762), and then analyzed by flow cytometry.
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