Home Antibody All anti-SH2B3 antibodies
Also for SH2B3 (NM_005475)
|Peptide with sequence NGPALQPSSPC, from the N Terminus of the protein sequence according to NP_005466.1.|
|Test: Human. Expected from seq similarity: Human
||ELISA: 1:64,000. WB: 0.3-1.0 µg/ml.
|Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.|
|Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
|Homo sapiens SH2B adaptor protein 3 (SH2B3), transcript variant 1|
Entrez Gene 10019 Human
|T-cell activation requires stimulation of the T-cell receptor (TCR; see MIM 186880)-CD3 (see CD3Z; MIM 186780) complex, followed by recruitment of an array of intracellular signaling proteins (e.g., GRB2 (MIM 108355) and PLCG1 (MIM 172420)). Mediating the interaction between the extracellular receptors and intracellular signaling pathways are adaptor proteins such as LAT (MIM 602354), TRIM (MIM 604962), and LNK.[supplied by OMIM]. |
| Neurotrophin signaling pathway|
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TA302531 (0.3µg/ml) staining of MOLT4 lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.