Anti-SERPINB6 Antibody, clone 1C5

Also for SERPINB6 (NM_004568)

OriGene Data

Immunogen	Full length human recombinant protein of human SERPINB6(NP_004559) produced in HEK293T cell.
Clone Name	clone 1C5	Isotype	IgG2a
Species Reactivity	Human , Monkey , Mouse	Concentration	0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *	WB, IHC, FC	Suggested Dilutions	WB 1:500~2000, IHC 1:150, FLOW 1:100,
Buffer	PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification	Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens serpin peptidase inhibitor, clade B (ovalbumin), member 6 (SERPINB6), transcript variant 1
Alternative Name	CAP; DFNB91; MSTP057; PI-6; PI6; PTI; SPI3
Database Link	NP_004559
Function	The protein encoded by this gene is a member of the serpin (serine proteinase inhibitor) superfamily, and ovalbumin(ov)-serpin subfamily. It was originally discovered as a placental thrombin inhibitor. The mouse homolog was found to be expressed in the hair cells of the inner ear. Mutations in this gene are associated with nonsyndromic progressive hearing loss, suggesting that this serpin plays an important role in the inner ear in the protection against leakage of lysosomal content during stress, and that loss of this protection results in cell death and sensorineural hearing loss. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq].
Related Pathway

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WB Image

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SERPINB6 (RC200668, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SERPINB6.

WB Image

Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-SERPINB6 monoclonal antibody.

IHC Image

Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-SERPINB6 mouse monoclonal antibody. (TA504127)

IHC Image

Immunohistochemical staining of paraffin-embedded Human liver tissue using anti-SERPINB6 mouse monoclonal antibody. (TA504127)

IHC Image

Immunohistochemical staining of paraffin-embedded Human endometrium tissue using anti-SERPINB6 mouse monoclonal antibody. (TA504127)

IHC Image

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-SERPINB6 mouse monoclonal antibody. (TA504127)

IHC Image

Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-SERPINB6 mouse monoclonal antibody. (TA504127)

FC Image

HEK293T cells transfected with either RC200668 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-SERPINB6 antibody(TA504127), and then analyzed by flow cytometry.

FC Image

Flow cytometric Analysis of Jurkat cells, using anti-SERPINB6 antibody(TA504127),(Red), compared to a nonspecific negative control antibody,(Blue).

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Anti-SERPINB6 TrueMAB Antibody clone 1C5

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

OriGene Data

Reference Data