Home Antibody All anti-SERPINB5 antibodies
Anti-SERPINB5 GAT Antibody Polyclonal
Generated by Genomic Immunization
Also for SERPINB5 (NM_002639)
|DNA immunization. This antibody is specific for the C Terminus Region of the target protein.|
|WB, ELISA, IHC
|| WB 1:20000, IHC 1:150,ELISA 1:100-1:2000
|20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0|
|The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
|This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT
|Homo sapiens serpin peptidase inhibitor, clade B (ovalbumin), member 5 (SERPINB5)|
Entrez Gene 5268 Human
|Maspin is structurally a serine protease inhibitor (serpin) that was initially isolated from normal human mammary epithelial cells. Serpins are a family of proteins that inhibit chymotrypsin-like serine proteinases. Serpins control activated proteinases and several are involved in the regulation of cell death. Maspin is found in the extracellular matrix and at the plasma membrane. Maspin has been shown to act at the cell surface to block cell motility and inhibit invasion of breast and prostate cancer cells. Maspin is present in normal mammary epithelial cells but is absent in many tumor cell lines, yet no major structural alterations of the Maspin gene have been identified in tumor cells. Similarly, Maspin is expressed in normal prostate cells and downregulated or absent in prostate tumor cells.|
|Secreted ProteinDruggable Genome p53 signaling pathway|
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SERPINB5 (RC224287, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SERPINB5.
Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-SERPINB5 Rabbit Polyclonal antibody. (TA590676)
Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-SERPINB5 Rabbit Polyclonal antibody. (TA590676)