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Anti-SDC1 GAT Antibody Polyclonal
Generated by Genomic Immunization
Also for SDC1 (NM_002997)
|DNA immunization. This antibody is specific for the Middle Region of the target protein.|
|20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0|
|The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
|This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT
|Homo sapiens syndecan 1 (SDC1), transcript variant 2|
|CD138; SDC; SYND1; syndecan|
|CD138 / Syndecan 1 is a transmembrane heparin sulphate proteoglycanwhich is made up of one core protein and five glycosaminoglycan. CD138 isexpected to play a role in cell adhesion. It is expressed on the surface of pre B cells and plasma cells but is absent from mature B cells. It is a selective marker for B cell lymphoblastic leukemia and lymphoplasmocytoid leukemia. It is lost from the apoptotic myeloma cells; hence is a useful marker for viable myeloma cells.This antibody stains all plasma cells and plasma cell lines. No staining of other leucocytes is seen in peripheral blood or bone marrow, although some ALL cell lines express the antigen weakly. Some staining of epithelial and endothelial cells may be seen in immunohistology.|
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