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Home Antibody All anti-SCARB1 antibodies

Anti-SCARB1 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA306788 Rabbit Polyclonal SCARB1 Antibody 100ug $325 In Stock
LC425949 SCARB1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for SCARB1 (NM_001082959)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenSCARB1 antibody was raised against a 15 amino acid peptide near the amino terminus of human SCARB1.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1 - 2 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens scavenger receptor class B, member 1 (SCARB1), transcript variant 2
Alternative NameCD36L1; CLA-1; CLA1; HDLQTL6; SR-BI; SRB1
Database LinkNP_001076428
Entrez Gene 949 Human
Entrez Gene 20778 Mouse
Entrez Gene 25073 Rat
FunctionScavenger receptor class B member 1 (SCARB1), also known as SR-BI, is part of the scavenger receptor superfamily, which is composed of many members with diverse structures, expression patterns, and functions. SCARB1 is a multi-ligand cell-surface receptor that mediates the selective uptake of lipid from HDL cholesterol into cells and is expressed in steroidogenic tissues in adult animals. Other ligands of SCARB1 include native, acetylated, or oxidized LDL and anionic phospholipids. SCARB1-deficient mice have elevated HDL levels and increased susceptibility to atherosclerosis on fat feeding, indicating its importance in the regulation of cholesterol homeostasis. Along with CLDN1, LDL-R, and the tetraspanin superfamily member CD81, SCARB1 has been reported to be an entry factor for the Hepatitis C virus. At least two isoforms of SCARB1 are known to exist.
Related PathwayTransmembraneDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of SCARB1 in human spleen tissue lysate with SCARB1 antibody at (A) 1 and (B) 2 ug/ml.
Immunohistochemistry of SCARB1 in human spleen tissue with SCARB1 antibody at 2.5 ug/ml.


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