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Home Antibody All anti-SCARB1 antibodies

Anti-SCARB1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306788
  • Rabbit Polyclonal SCARB1 Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC425949) , 20ug
100ug 325 In Stock
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WB(1)
IHC(1)
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Also for SCARB1 (NM_001082959)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenSCARB1 antibody was raised against a 15 amino acid peptide near the amino terminus of human SCARB1.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1 - 2 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens scavenger receptor class B, member 1 (SCARB1), transcript variant 2
Alternative NameCD36L1; CLA-1; CLA1; HDLQTL6; SR-BI; SRB1
Database LinkNP_001076428
FunctionScavenger receptor class B member 1 (SCARB1), also known as SR-BI, is part of the scavenger receptor superfamily, which is composed of many members with diverse structures, expression patterns, and functions. SCARB1 is a multi-ligand cell-surface receptor that mediates the selective uptake of lipid from HDL cholesterol into cells and is expressed in steroidogenic tissues in adult animals. Other ligands of SCARB1 include native, acetylated, or oxidized LDL and anionic phospholipids. SCARB1-deficient mice have elevated HDL levels and increased susceptibility to atherosclerosis on fat feeding, indicating its importance in the regulation of cholesterol homeostasis. Along with CLDN1, LDL-R, and the tetraspanin superfamily member CD81, SCARB1 has been reported to be an entry factor for the Hepatitis C virus. At least two isoforms of SCARB1 are known to exist.
Related Pathway

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WB Image
Western blot analysis of SCARB1 in human spleen tissue lysate with SCARB1 antibody at (A) 1 and (B) 2 ug/ml.
IHC Image
Immunohistochemistry of SCARB1 in human spleen tissue with SCARB1 antibody at 2.5 ug/ml.

 

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