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Home All anti-SCARB1 antibodies

Anti-SCARB1 Antibody

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA301489
  • Rabbit Polyclonal Antibody against SR-BI
  • FREE positive control: HEK293T cell transient overexpression lysate (LC401684) , 20ug
100ul $325 In Stock Add to Shopping Cart
WB(2)
IHC(1)
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Also for SCARB1 (NM_005505)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
Gene NameHomo sapiens scavenger receptor class B, member 1 (SCARB1), transcript variant 1
Synonyms:CD36L1; CLA-1; CLA1; HDLQTL6; SR-BI; SRB1
ImmunogenA C-terminal peptide containing residues from mouse Scavenger Receptor-BI (within residues 450-509).
BufferTris-citrate/phosphate [pH 7-8] buffer. and 0.1% Sodium Azide
Clone Name Isotypen/a
Species Reactivityhuman, mouse, rat, mink, hamster Concentration3.0 mg/ml
Purification Affinity purified (Protein A or G Sepharose)
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1: 1000-1:5000
BackgroundHigh density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. The SR-BI binds HDLs and mediates selective uptake of HDL cholesteryl ester. SR-BI binds HDL with high affinity, is expressed primarily in liver and nonplacental steroidgenic tissues, and mediates selective cholesterol uptake by a distinct mechanism. In mice, it seems that SR-BI plays a key role in determining the levels of plasma lipoprotein cholesterol and the accumulation of cholesterol stores in the adrenal gland.
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control or pCMV6-ENTRY SCARB1 (RC210264) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SCARB1.
WB Image
Detection of SR-BI in 25 ug of mouse liver lysate, using anti-SRBI at a 1:1,000 dilution, shows distinct band at 82 kDa.
IHC Image
Staining of adrenal, cortex

 

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