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Anti-EDG1 Antibody EPR4538(2)
Also for EDG1 (NM_001400)
|A synthetic peptide corresponding to residues near the N-terminus of human EDG1 was used as an immunogen.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:10000 - 1:50000
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
|Homo sapiens sphingosine-1-phosphate receptor 1 (S1PR1)|
|CD363; CHEDG1; D1S3362; ECGF1; EDG-1; EDG1; S1P1|
|EDG1 is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion (1).|
Signaling by GPCR
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Western blot - Anti-EDG1 antibody [EPR4538(2)]; All lanes : Anti-EDG1 antibody [EPR4538(2)] at 1/10000 dilution.Lane 1 : Jurkat cell lysate.Lane 2 : SH-SY5Y cell lysate.Lane 3 : HUVEC cell lysate.Lane 4 : A375 cell lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 43 kDa.