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Home Antibody All anti-RPS6KA1 antibodies

Anti-RPS6KA1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA302100
  • Rabbit Polyclonal Antibody against RPS6KA1 (S732)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401035) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
IHC(1)
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Also for RPS6KA1 (NM_002953)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenThis RPS6KA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 710-735 amino acids from human RPS6KA1.
Clone Name IsotypeRabbit Ig
Species ReactivityHuman (Predicted: Mouse, Rat) Concentration0.25 mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000, IHC: 1:10~50
Predicted MW Explanation 82723 Da
BufferPurified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.

Reference Data

Target NameHomo sapiens ribosomal protein S6 kinase, 90kDa, polypeptide 1 (RPS6KA1), transcript variant 1
Alternative NameHU-1; MAPKAPK1A; RSK; RSK1
Database LinkNP_002944
Entrez Gene 6195 Human
Entrez Gene 20111 Mouse
Entrez Gene 81771 Rat
FunctionRPS6KA1 is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation.
Related PathwayProtein KinaseDruggable Genome MAPK signaling pathwayOocyte meiosismTOR signaling pathwayLong-term potentiationNeurotrophin signaling pathwayProgesterone-mediated oocyte maturationMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of RPS6KA1 (arrow) using rabbit polyclonal RPS6KA1 Antibody (S732). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the RPS6KA1 gene (Lane 2) (Origene Technologies).
IHC Image
Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with RPS6KA1 Antibody (S732), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

 

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