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Home Antibody All anti-RPS6KA1 antibodies

Anti-RPS6KA1 Antibody E4

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA300902
  • Rabbit Monoclonal Antibody against RPS6KA1 (Clone E4)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401035) , 20ug
100ul 325 3-7 Days
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WB(1)
IHC(1)
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Also for RPS6KA1 (NM_002953)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in N-terminus of human p90-RSK1 was used as immunogen.
Clone NameE4 IsotypeIgG
Species ReactivityHuman, Mouse, Rat ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000; IHC-P: Use at an assay dependent dilution; ICC: 1:200; FC: 1:50; IP: 1:10
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%

Reference Data

Target NameHomo sapiens ribosomal protein S6 kinase, 90kDa, polypeptide 1 (RPS6KA1), transcript variant 1
Alternative NameHU-1; MAPKAPK1A; RSK; RSK1
Database LinkNP_002944
FunctionRSK 1 (p90-RSK 1) is a member of a family of 90 kDa ribosomal protein S6 kinases, which includes RSK 1, RSK 2 and RSK 3. These are broadly expressed serine/threonine protein kinases (1) activated in response to mitogenic stimuli, including extracellular signal-regulated protein kinases Erk1 and Erk2 (2). p90-RSK 1 is activated by MAPK in vitro and in vivo via phosphorylation (3). Active RSKs appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c-Fos and CREB (2,4).
Related Pathway
EGFR1 Signaling Pathway
MAPK signaling pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-RSK1 p90 antibody [E4]; Anti-RSK1 p90 antibody [E4] at 1/1000 dilution + MCF7 cell lysate at 10 µg.Predicted band size : 83 kDa.Observed band size : 90 kDa .
IHC Image
Immunohistochemistry (Paraffin-embedded sections) - RSK1 p90 antibody [E4]; Ab32114, at a 1/100 dilution, staining RSK1 p90 in paraffin embedded human colon tissue by immunohistochemistry.

 

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