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Home Antibody All anti-RPS6 antibodies

Anti-RPS6 PHOSPHO Antibody

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SKU Description Amount Price Availability*  
TA323449 Anti-RPS6 (Phospho-Ser235) Rabbit Polyclonal Antibody 100ul $325 2-3 Weeks

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

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WB(1)
IF(1)

OriGene Data

ImmunogenPeptide sequence around phosphorylation site of serine 235 (R-L-S(p)-S-L) derived from Human S6 Ribosomal Protein.
Clone Name IsotypeIgG
Species ReactivityHuman; Mouse; Rat Concentration1mg/ml
Guaranteed Application *WB, IF Suggested DilutionsWB: 1:500-1000, IF: 1:100-200
Predicted MW Explanation 32kDa
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens ribosomal protein S6 (RPS6)
Alternative NameS6
Database LinkNP_001001
Entrez Gene 6194 Human
Entrez Gene 20104 Mouse
Entrez Gene 29304 Rat
FunctionRibosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Related Pathway RibosomemTOR signaling pathwayInsulin signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Predicted band size: 32 kDa . Positive control: PC12 cells treated with anisomycin lysate. Recommended dilution: 1/ 500-1000. (Gel: 10%SDS-PAGE Lane1: PC12 cells untreated with anisomycin lysate Lane2: PC12 cells treated with anisomycin lysate Lysates: 30 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute)
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Predicted cell location: Cytoplasm. Positive control: Hela cells. Recommended dilution: 1/ 100-200.The image is immunofluorescence of methanol-fixed Hela cells using RPS6 (Phospho-Ser235) antibody at dilution 1/100. (Original magnification:×200)
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