ROCK2 belongs to the protein kinase superfamily, and it is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1, is a target for the small GTPase Rho (1,2).
Signaling by GPCR
TGF Beta Signaling Pathway
Wnt Signaling Pathway
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