Home Antibody All anti-ROBO3 antibodies
Also for ROBO3 (NM_022370)
| Peptide with sequence C-RRKQRKELSHYT, from the internal region of the protein sequence according to NP_071765.2.|
|Test: Human. Expected from seq similarity: Human, Dog, Pig, Cow
||ELISA: 1:32,000. WB: 0.5-1µg/ml.
|Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.|
| Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
|Homo sapiens roundabout, axon guidance receptor, homolog 3 (Drosophila) (ROBO3)|
|HGPPS; HGPS; RBIG1; RIG1|
Entrez Gene 64221 Human
Entrez Gene 489307 Dog
|Thought to be involved during neural development in axonal navigation at the ventral midline of the neural tube. In spinal chord development plays a role in guiding commissural axons probably by preventing premature sensitivity to Slit proteins thus inhibiting Slit signaling through ROBO1 (By similarity). Required for hindbrain axon midline crossing|
|Druggable Genome Axon guidance|
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TA303233 (0.5µg/ml) staining of Human Brain (Cerebellum) lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.