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Anti-RNH1 TRUEMAB Antibody Clone OTI4G4

TrueMAB™ Antibodies - Made against Authentic Protein Antigens


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA501874 RNH1 (Ribonuclease Inhibitor) mouse monoclonal antibody, clone OTI4G4 (formerly 4G4) 100ul 325
In Stock
LC401028 RNH1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF501874 Carrier-free (BSA/glycerol-free) RNH1 mouse monoclonal antibody, clone OTI4G4 (formerly 4G4) 100ug $450 3 Days
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OriGene Data

ImmunogenFull length human recombinant protein of human RNH1 (NP_002930) produced in HEK293T cell.
Clone NameClone OTI4G4 IsotypeIgG1
Species ReactivityHuman Concentration0.83 mg/ml
Guaranteed Application *WB, IHC, IF, FC Suggested DilutionsWB 1:2000, IF 1:100, FLOW 1:100, IHC: 1:150
Predicted MW Explanation 49.8 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens ribonuclease/angiogenin inhibitor 1 (RNH1), transcript variant 1
Alternative NameRAI; RNH
Database LinkNP_002930
Entrez Gene 6050 Human
FunctionPlacental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular RNases (summarized by Lee et al., 1988 [PubMed 3219362]). In addition to control of intracellular RNases, the inhibitor may have a role in the regulation of angiogenin (MIM 105850). Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases probably play a critical role in the turnover of RNA in eukaryotic cells, RNH may be essential for control of mRNA turnover; the interaction of eukaryotic cells with ribonuclease may be reversible in vivo.[supplied by OMIM].
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RNH1 (RC208360, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-RNH1.
Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-RNH1 mouse monoclonal antibody. (TA501874)
Anti-RNH1 mouse monoclonal antibody (TA501874) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY RNH1(RC208360).
HEK293T cells transfected with either RC208360 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-RNH1 antibody(TA501874), and then analyzed by flow cytometry.
Flow cytometric Analysis of Hela cells, using anti-RNH1 antibody(TA501874),(Red), compared to a nonspecific negative control antibody(TA50011),(Blue).


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