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Home Antibody All anti-RIPK3 antibodies

Anti-RIPK3 TRUEMAB Antibody Clone 2F12

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA803171
  • RIPK3 mouse monoclonal antibody,clone 2F12
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC416351) , 20ug Explanation
100ul 325 In Stock
CF803171
  • Carrier-free (BSA/glycerol-free) RIPK3 mouse monoclonal antibody,clone 2F12
100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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WB(1)
IHC(2)

OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 233-518 of human RIPK3 (NP_006862) produced in E.coli.
Clone NameClone 2F12 IsotypeIgG1
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IHC Suggested Dilutions WB 1:2000, IHC 1:150,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens receptor-interacting serine-threonine kinase 3 (RIPK3)
Alternative NameRIP3
Database LinkNP_006862
Entrez Gene 11035 Human
FunctionThe product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. [provided by RefSeq, Jul 2008].
Related PathwayProtein KinaseDruggable Genome Cytosolic DNA-sensing pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RIPK3 (RC209549, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-RIPK3.
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-RIPK3 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA803171)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-RIPK3 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA803171)

 

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