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Anti-RIPK3 TRUEMAB Antibody Clone OTI2B10
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for RIPK3 (NM_006871)
|Human recombinant protein fragment corresponding to amino acids 233-518 of human RIPK3 (NP_006862) produced in E.coli.|
||WB 1:200 -1:2000, IHC 1:150,
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens receptor-interacting serine-threonine kinase 3 (RIPK3)|
Entrez Gene 11035 Human
|The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. [provided by RefSeq, Jul 2008]. |
|Protein KinaseDruggable Genome Cytosolic DNA-sensing pathway|
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RIPK3 (RC209549, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-RIPK3.
Western blot analysis of extracts (10ug) from 2 different cell lines by using anti-RIPK3 monoclonal antibody at 1:200.
Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-RIPK3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA803093)
Immunohistochemical staining of paraffin-embedded Human Ovary tissue within the normal limits using anti-RIPK3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA803093)