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Home Antibody All anti-RHOA antibodies

Anti-RHOA Antibody EP487Y

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA300589
  • Rabbit Monoclonal Antibody against RHOA (Clone EP487Y)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400630) , 20ug
100ul $325 In Stock
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WB(1)
IHC(1)
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Also for RHOA (NM_001664)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the N-term of human Rho was used as immunogen. The antibody is predicted to detect RhoA, RhoB and RhoC based on sequence analysis.
Clone NameEP487Y IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:2,000-10,000; IHC: 1: 100-250; ICC: 1:250-500; IP: 1:50
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant

Reference Data

Target NameHomo sapiens ras homolog family member A (RHOA)
Alternative NameARH12; ARHA; RHO12; RHOH12
Database LinkNP_001655
FunctionRho belongs to the Ras super family of low molecular weight GTPases. Fifteen Rho proteins have already been characterized and divided into three sub-families; the first includes Rho (A, B, C), the second, Rnd 1-3 and the third which includes Rac 1-3, RhoG, Cdc42Hs, Rho/TTF. TC10 and Chp (1-2). Rho acts as a molecular switch which turns on of off various intracellular signaling pathways such as ACK, PAKs, MEKKs ROCK (3). Rho is active when bound to GTP and inactive when bound to GDP (4). It is also known to participate in many physiological activities including cell migration, adhesion, cytokinesis, proliferation, differentiation and apoptosis and to a greater extend cell transformation (5).
Related Pathway
Adherens junction
Focal Adhesion
Signaling by GPCR
TGF Beta Signaling Pathway
Wnt Signaling Pathway

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WB Image
Western blot - Rho antibody [EP487Y]; Anti-Rho antibody [EP487Y] + 10ug HL60 cell lysate.Predicted band size : 21 kDa.Observed band size : 22 kDa .
IHC Image
Immunohistochemistry (Paraffin-embedded sections) - Rho antibody [EP487Y]; TA300589 at a 1:100 dilution staining Rho in human prostate carcinoma tissue.

 

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