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Home Antibody All anti-RHEB antibodies

Anti-RHEB Antibody EPR2971

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307202
  • Rabbit monoclonal antibody against Rheb (clone EPR2971 )
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC417187) , 20ug
100ul 325 3-7 Days
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WB(1)
IHC(1)
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Also for RHEB (NM_005614)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Rheb was used as an immunogen.
Clone NameEPR2971 IsotypeIgG
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsFC: 1:100, ICC: 1:100 - 250, IHC: 1:100 - 250, WB: 1:2000 - 5000,
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens Ras homolog enriched in brain (RHEB)
Alternative NameRHEB2
Database LinkNP_005605
FunctionRheb (Ras Homolog Enriched in brain) is a Ras-like small guanosine triphosphatase (GTPase) that is involved in cell growth and cell cycle progression. Rheb has also been suggested to have involvement in the TOR/S6K signaling pathway (1). It regulates the activity of the mammalian target of rapamycin, mTOR, a central regulator of cell growth, in response to growth factor stimulation and nutrient availability (2). It also interacts with and appears to regulate Raf-1 kinase, an essential component of the H-Ras signaling pathway, and is suggested to function in concert with H-Ras to dynamically integrate cAMP and growth factor signaling (3).
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - RHEB antibody [EPR2971]; All lanes : Anti-RHEB antibody [EPR2971] at 1/2000 dilution.Lane 1 : Raji cell lsyate.Lane 2 : SH-SY5Y cell lsyate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 20 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - RHEB antibody [EPR2971]; TA307202, at 1/100 dilution, staining RHEB in paraffin-embedded Human brain tissue, by Immunohistochemistry.

 

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