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Anti-REN Antibody EPR6433
|A synthetic peptide corresponding to residues in human Renin was used as an immunogen.|
||Tissue culture supernatant
||Lot dependent; please refer to CoA along with shipment
|WB, ASSAY, FC
||WB: 1:1000 - 1:10000; FC: 1:10 - 1:100
|Does not react with Mouse, Rat. Is unsuitable for ICC,IHC-P or IP.|
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
|Is unsuitable for ICC,IHC-P or IP.
|Homo sapiens renin (REN)|
|Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release, vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Mutations in Renin have been shown to cause familial hyperproreninemia (1). |
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Western blot - Anti-Prorenin antibody [EPR6433]; All lanes : Anti-Prorenin antibody [EPR6433] at 1/1000 dilution.Lane 1 : K562 lysate.Lane 2 : 293T lysate.Lane 3 : HepG2 lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 45 kDa.Observed band size : 47 kDa .
Other-Anti-Prorenin antibody [EPR6433](TA311049); Equilibrium disassociation constant (KD)..
Flow Cytometry - Anti-Prorenin antibody [EPR6433]; Flow cytometric analysis of permeabilized K562 cells using TA311049 at 1/10 shown in red or a rabbit IgG negative control shown in green.