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Home Antibody All anti-REN antibodies

Anti-REN Antibody EPR6433

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA311049
  • Rabbit Monoclonal antibody against Renin (REN)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424660) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
FC(1)
Assay(1)
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Also for REN (NM_000537)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Renin was used as an immunogen.
Clone NameEPR6433 IsotypeTissue culture supernatant
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY, FC Suggested DilutionsWB: 1:1000 - 1:10000; FC: 1:10 - 1:100
BufferDoes not react with Mouse, Rat. Is unsuitable for ICC,IHC-P or IP.
Purification pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Note Is unsuitable for ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens renin (REN)
Alternative NameHNFJ2
Database LinkNP_000528
Entrez Gene 5972 Human
FunctionRenin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release, vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Mutations in Renin have been shown to cause familial hyperproreninemia (1).
Related PathwaySecreted ProteinDruggable Genome Renin-angiotensin system

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-Prorenin antibody [EPR6433]; All lanes : Anti-Prorenin antibody [EPR6433] at 1/1000 dilution.Lane 1 : K562 lysate.Lane 2 : 293T lysate.Lane 3 : HepG2 lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 45 kDa.Observed band size : 47 kDa .
Assay Image
Other-Anti-Prorenin antibody [EPR6433](TA311049); Equilibrium disassociation constant (KD)..
FC Image
Flow Cytometry - Anti-Prorenin antibody [EPR6433]; Flow cytometric analysis of permeabilized K562 cells using TA311049 at 1/10 shown in red or a rabbit IgG negative control shown in green.

 

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