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 Home All anti-RB1 antibodies

Anti-RB1 Phospho Antibody E231

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA303683
  • Rabbit monoclonal antibody against Rb Phospho (pT821) (E231 ) (phospho-specific)
100µl $325 3-7 Days
TA802519S
  • Purified GAPDH mouse monoclonal antibody (Loading control), clone 2D9
 30ul
$100
$50*		 In Stock
Add to Shopping Cart
* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
WB(1)
IF(1)

OriGene Data

ImmunogenA synthetic phospho-peptide corresponding to residues surrounding Thr821 of human Rb was used as immunogen. The antibody only detects Rb phosphorylated on Threonine 821.
Clone NameE231 IsotypeRabbit IgG
Species ReactivityHuman Concentration
Guaranteed Application *WB, IF Suggested DilutionsWB: 1:1,000; ICC: 1:100; IP: 1:20
Buffer50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

Reference Data

Target NameHomo sapiens retinoblastoma 1 (RB1)
Alternative NameOSRC; p105-Rb; pp110; pRb; RB
Database LinkNP_000312
FunctionThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq].
Related Pathway
Adipogenesis
Cell cycle
Senescence and Autophagy
TGF Beta Signaling Pathway

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WB Image
Western blot analysis on Jurkat cell lysates using anti-Phospho-Rb (pT821) RabMAb (TA303683); dilution 1:1,000. Cells were (1) untreated, and (2) treated with Phosphatase.
IF Image
Immunofluorescent analysis of HeLa cells using anti-Phospho-Rb (pT821) RabMAb (TA303683).

 

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