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Home Antibody All anti-RB1 antibodies

Anti-RB1 PHOSPHO Antibody E231

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303683
  • Rabbit monoclonal antibody against Rb Phospho (pT821) (E231 ) (phospho-specific)
100ul 325 3-7 Days
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WB(1)
IF(1)

OriGene Data

ImmunogenA synthetic phospho-peptide corresponding to residues surrounding Thr821 of human Rb was used as immunogen. The antibody only detects Rb phosphorylated on Threonine 821.
Clone NameE231 IsotypeIgG
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IF Suggested DilutionsWB: 1:1000 - 1:10000; ICC/IF: 1:100; IP: 1:20
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens retinoblastoma 1 (RB1)
Alternative NameOSRC; p105-Rb; pp110; pRb; RB
Database LinkNP_000312
FunctionThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq].
Related Pathway
Adipogenesis
Cell cycle
Senescence and Autophagy
TGF Beta Signaling Pathway

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WB Image
Western blot - Rb (phospho T821) antibody [E231]; All lanes : Anti-Rb (phospho T821) antibody [E231] at 1/1000 dilution.Lane 1 : Jurkat cell lysate, untreated.Lane 2 : Jurkat cell lysate treated with Phosphatase.Predicted band size : 106 kDa.Observed band size : 110 kDa .
IF Image
Immunofluorescence - Rb (phospho T821) antibody [E231]; Ab32015, at a 1/100 dilution, staining Rb in HeLa cells by Immunofluorescence.

 

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