OriGene Technologies, Inc.
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-RASSF1 antibodies

Anti-RASSF1 TRUEMAB Antibody Clone OTI2B11

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

div

Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA502449 RASSF1 mouse monoclonal antibody, clone OTI2B11 (formerly 2B11) 100ul $379 In Stock
LC402099 RASSF1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF502449 Carrier-free (BSA/glycerol-free) RASSF1 mouse monoclonal antibody, clone OTI2B11 (formerly 2B11) 100ug $450 3-4 weeks
Add to Shopping Cart

spacer
WB(1)
IHC(12)
IF(1)
FC(1)

OriGene Data

ImmunogenFull length human recombinant protein of human RASSF1 (NP_009113) produced in E.coli.
Clone NameClone OTI2B11 IsotypeIgG1
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IHC, IF, FC Suggested DilutionsWB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100
Predicted MW Explanation 38.6 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens Ras association (RalGDS/AF-6) domain family member 1 (RASSF1), transcript variant A
Alternative Name123F2; NORE2A; RASSF1A; RDA32; REH3P21
Database LinkNP_009113
Entrez Gene 11186 Human
FunctionThis gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Seven alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Related PathwayDruggable Genome Pathways in cancerBladder cancerNon-small cell lung cancer

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RASSF1 (RC213525, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-RASSF1.
spacer
Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-RASSF1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502449)
spacer
Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-RASSF1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502449)
spacer
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-RASSF1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502449)
spacer
Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-RASSF1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502449)
spacer
Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-RASSF1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502449)
spacer
Immunohistochemical staining of paraffin-embedded Human endometrium tissue within the normal limits using anti-RASSF1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502449)
spacer
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-RASSF1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502449)
spacer
Immunohistochemical staining of paraffin-embedded Human prostate tissue within the normal limits using anti-RASSF1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502449)
spacer
Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-RASSF1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502449)
spacer
Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-RASSF1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502449)
spacer
Immunohistochemical staining of paraffin-embedded Human lymph node tissue within the normal limits using anti-RASSF1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502449)
spacer
Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-RASSF1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502449)
spacer
Anti-RASSF1 mouse monoclonal antibody (TA502449) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY RASSF1(RC213525).
spacer
HEK293T cells transfected with either RC213525 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-RASSF1 antibody(TA502449), and then analyzed by flow cytometry.
spacer

 

spacer
Inc 5000 Healthcare Company
All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title