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Home Antibody All anti-RARA antibodies

Anti-RARA Antibody EP1823Y

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA300976
  • Rabbit Monoclonal Antibody against RARA (Clone EP1823Y)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400350) , 20ug
100ul 325 3-7 Days
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WB(1)
FC(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near N-terminal of human RAR alpha protein was used as an immunogen.
Clone NameEP1823Y IsotypeTissue culture supernatant
Species ReactivityMouse, Human (Does not react with: Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, FC Suggested DilutionsWB: 1:500 - 1:1000; FC: 1:50
BufferDoes not react with Rat. Is unsuitable for ICC,IHC-P or IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens retinoic acid receptor, alpha (RARA), transcript variant 1
Alternative NameNR1B1; RAR
Database LinkNP_000955
FunctionThe retinoic acid receptors (RARs) are family of nuclear receptors that mediates effects of retinoic acid (RA, acidified form of vitamin A), a non-steroid hormone involved in cell proliferation, differentiation, and apoptosis (1). Three isoforms of RAR exists (RAR alpha, beta, and gamma) and forms a heterodimer with RXRs (retinoid X receptor, a distant related receptor). When bound to RA, RARs acts as transcription factors and binds to thyroid hormone response element or RA response element (RARE), activating gene expression (2). RAR alpha has been implicated as important biomedical marker in the pathogenesis of acute promyelocytic leukemia (APL) (3).
Related Pathway
Adipogenesis

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Retinoic Acid Receptor alpha antibody [EP1823Y]; Anti-Retinoic Acid Receptor alpha antibody [EP1823Y] at 1/1000 dilution + MCF-7 cell lysate at 10 ug.Predicted band size : 51 kDa.Observed band size : 55 kDa .
FC Image
Flow Cytometry - Retinoic Acid Receptor alpha antibody [EP1823Y]; Flow cytometric analysis of permeabilized MCF-7 cells using TA300976 at 1/50 dilution (red) or a rabbit IgG (negative) (green).

 

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