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Home Antibody All anti-RAPGEF1 antibodies

Anti-RAPGEF1 TRUEMAB Antibody Clone OTI1B2

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA506822 RAPGEF1 mouse monoclonal antibody, clone OTI1B2 (formerly 1B2) 100ul $325 In Stock
LC404802 RAPGEF1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF506822 Carrier-free (BSA/glycerol-free) RAPGEF1 mouse monoclonal antibody, clone OTI1B2 (formerly 1B2) 100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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WB(1)
IHC(1)

OriGene Data

ImmunogenFull length human recombinant protein of human RAPGEF1(NP_941372) produced in HEK293T cell.
Clone NameClone OTI1B2 IsotypeIgG1
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IHC Suggested Dilutions WB 1:4000, IHC: 1:150
Predicted MW Explanation 122.6 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens Rap guanine nucleotide exchange factor (GEF) 1 (RAPGEF1), transcript variant 2
Alternative NameC3G; GRF2
Database LinkNP_941372
Entrez Gene 2889 Human
FunctionThis gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008].
Related PathwayDruggable Genome Focal adhesionNeurotrophin signaling pathwayInsulin signaling pathwayRenal cell carcinoma

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RAPGEF1 (RC208092, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-RAPGEF1.
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Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-RAPGEF1 mouse monoclonal antibody. (TA506822)
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