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Anti-RAP1A Antibody Polyclonal
Also for RAP1A (NM_001010935)
|A synthetic peptide corresponding to residues near the N-terminus of human Rap1 was used as an immunogen.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:5000; FC: 1:20; IHC-P: Use at an assay dependent dilution
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Protein A purified (Protein A or G Sepharose)
|Homo sapiens RAP1A, member of RAS oncogene family (RAP1A), transcript variant 1|
|KREV-1; KREV1; RAP1; SMGP21|
|The product of this gene belongs to the family of RAS-related proteins. These proteins share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. The product of this gene counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq]. |
MAPK signaling pathway
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Western blot - RAP1A + RAP1B antibody; Anti-RAP1A + RAP1B antibody at 1/5000 dilution + C6 cell lysate.Predicted band size : 21 kDa.Observed band size : 21 kDa.
Immunohistochemistry (Paraffin-embedded sections) - RAP1A + RAP1B antibody; Ab40814 staining human RAP1A + RAP1B in human cervical carcinoma by immunohistochemistry using paraffin embedded tissue.