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OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431. [anti-DDK]
Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780. [SARM1]
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052 [anti-DDK]
Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210. [NPR3]
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 Home All anti-RANGAP1 antibodies

Anti-RANGAP1 Antibody EPR3295

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA310812
  • Rabbit Monoclonal antibody against RanGAP1
  • FREE positive control: HEK293T cell transient overexpression lysate (LC401016) , 20ug
 100ul $325 3-7 Days Add to Shopping Cart
WB(1)
IHC(2)
IF(2)
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Also for RANGAP1 (NM_002883)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
Gene NameHomo sapiens Ran GTPase activating protein 1 (RANGAP1)
Synonyms:Fug1; SD
ImmunogenA synthetic peptide corresponding to residues in human RanGAP1 was used as an immunogen.
BufferStore at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
Clone NameEPR3295 Isotype
Species ReactivityHuman, Mouse, Rat Concentration
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1:1,000 - 5,000; IHC 1:100 - 250; ICC: 1:100 - 250;
BackgroundRanGAP1 is the activator of the Ras-related nuclear GTPase Ran, which is involved in the nucleocytoplasmic transport, mitotic spindle assembly, cell cycle control and nuclear envelope (NE) formation (1, 2). Its roles are accomplished by the asymmetric distribution of its GTP- and GDP-bound forms, enabled by the specific localization of Ran accessory proteins, the Ran GTPase-activating protein RanGAP and the nucleotide exchange factor RCC. Mammalian RanGAP1 is targeted to the NE during interphase and to the spindle and kinetochores during mitosis via SUMOylated C-terminal domain and interaction with the nucleoporin Nup358/RanBP2 (2). RanGAP1 is highly expressed in brain, thymus and testis (3).
Related Pathway
Cell cycle

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis on (A) HeLa, (B) MCF-7, (C) SH-SY5Y and (D) A549 cell lysates using anti-RanGAP1 RabMAb.
IHC Image
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-RanGAP1 RabMAb.
IHC Image
Immunohistochemical analysis of paraffin-embedded human testis tissue using anti-RanGAP1 RabMAb.
IF Image
Western blot analysis on (A) HeLa, (B) MCF-7, (C) SH-SY5Y and (D) A549 cell lysates using anti-RanGAP1 RabMAb.
IF Image
Immunofluorescent staining of HeLa cells using anti-RanGAP1 RabMAb.

 

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