Home Antibody All anti-RANBP1 antibodies
Also for RANBP1 (NM_002882)
|Recombinant fragment corresponding to a region within amino acids 1 and 201 of Ran BP1 (Uniprot ID#P43487)|
|Human, Mouse (Predicted: Rat, Cow)
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Rat (97%), cow (88%)
|Homo sapiens RAN binding protein 1 (RANBP1), transcript variant 2|
Entrez Gene 5902 Human
Entrez Gene 19385 Mouse
Entrez Gene 360739 Rat
|Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92% similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN. [provided by RefSeq]|
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Sample (50 ug of whole cell lysate). A: Mouse brain. 12% SDS PAGE. TA308769 diluted at 1:1000.
Sample (30 ug of whole cell lysate). A: HeLa S3 . 12% SDS PAGE. TA308769 diluted at 1:1000
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using Ran BP-1 (TA308769) antibody at 1:200 dilution.