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Home Antibody All anti-RANBP1 antibodies

Anti-RANBP1 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA308769 Rabbit Polyclonal antibody to Ran BP1 (RAN binding protein 1) 100ul $325 3-7 Days
LC401015 RANBP1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for RANBP1 (NM_002882)
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OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 1 and 201 of Ran BP1 (Uniprot ID#P43487)
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse (Predicted: Rat, Cow) Concentration1mg/ml
Guaranteed Application *WB, IF Suggested DilutionsICC/IF:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 23kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Rat (97%), cow (88%)

Reference Data

Target NameHomo sapiens RAN binding protein 1 (RANBP1), transcript variant 2
Alternative NameHTF9A
Database LinkNP_002873
Entrez Gene 5902 Human
Entrez Gene 19385 Mouse
Entrez Gene 360739 Rat
FunctionRan/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92% similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN. [provided by RefSeq]
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample (50 ug of whole cell lysate). A: Mouse brain. 12% SDS PAGE. TA308769 diluted at 1:1000.

WB Image
Sample (30 ug of whole cell lysate). A: HeLa S3 . 12% SDS PAGE. TA308769 diluted at 1:1000

IF Image
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using Ran BP-1 (TA308769) antibody at 1:200 dilution.


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