Home Antibody All anti-RAMP2 antibodies
Also for RAMP2 (NM_005854)
|Synthetic peptide corresponding to a region within amino acids 111 and 175 of RAMP2 (Uniprot ID#O60895)|
|Human (Predicted: Mouse, Rat, Pig, Bovine)
||Lot dependent; please refer to CoA along with shipment
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Mouse (87%), Rat (80%), Pig (86%), Bovine (93%)
|Homo sapiens receptor (G protein-coupled) activity modifying protein 2 (RAMP2)|
Entrez Gene 10266 Human
Entrez Gene 54409 Mouse
Entrez Gene 58966 Rat
|The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP2) protein, CRLR functions as an adrenomedullin receptor. The RAMP2 protein is involved in core glycosylation and transportation of adrenomedullin receptor to the cell surface. [provided by RefSeq]|
|TransmembraneDruggable Genome Vascular smooth muscle contraction|
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RAMP2 antibody detects RAMP2 protein by Western blot analysis. A. 30 ug Jurkat whole cell lysate/extract. B. 30 ug Raji whole cell lysate/extract. C. 30 ug K562 whole cell lysate/extract. D. 30 ug THP-1 whole cell lysate/extract. E. 30 ug HL-60 whole cell
Immunohistochemical analysis of paraffin-embedded SG xenograft, using RAMP2(TA308436) antibody at 1:100 dilution.