Home Antibody All anti-RAE1 antibodies
Also for RAE1 (NM_001015885)
| Peptide with sequence C-NAAEELKPRNKK, from the C Terminus of the protein sequence according to NP_003601.1; NP_001015885.1.|
|Test: Human. Expected from seq similarity: Human, Mouse, Rat, Pig, Dog, Cow
||ELISA: 1:64,000. WB: 0.03-0.1µg/ml.
|Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.|
| Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
|Homo sapiens ribonucleic acid export 1 (RAE1), transcript variant 2|
|dJ481F12.3; dJ800J21.1; MIG14; Mnrp41; MRNP41|
Entrez Gene 8480 Human
Entrez Gene 66679 Mouse
Entrez Gene 362281 Rat
Entrez Gene 485942 Dog
|Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene. |
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TA303044 staining (0.03µg/ml) of HepG2 lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.