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Home Antibody All anti-RAD23A antibodies

Anti-RAD23A Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319249
  • Goat polyclonal anti-HR23A antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC417539) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
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Also for RAD23A (NM_001270362)
cDNA Clone shRNA/siRNA Primer Pair Protein Request Antibody

OriGene Data

ImmunogenThis affinity purified antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding aa 122-135 of human HR23A protein.
Clone Name Isotype
Species Reactivityhuman Concentration1.2 mg/mL
Guaranteed Application *WB Suggested DilutionsELISA: 1:4,000 - 1:16,000, WB: 1:500 - 1:2,000
Buffer0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Note HR23A (also known as UV excision repair protein RAD23 homolog A) is one of two human homologs of Saccharomyces cerevisiae Rad23 (hHR23A and hHR23B), a protein involved in nucleotide excision repair (NER). This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.

Reference Data

Target NameHomo sapiens RAD23 homolog A (S. cerevisiae) (RAD23A), transcript variant 2
Alternative NameHHR23A; HR23A
Database LinkNP_001257291
Entrez Gene 5886 Human
Function
Related PathwayDruggable Genome Nucleotide excision repair

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot showing Affinity Purified anti-HR23A antibody detects endogenous human HR23A. Reactivity is shown against HeLa nuclear extract (lane 1) and HeLa (lane 2), A431 (lane 3), Jurkat (lane 4) and 293 whole cell lysates (lane 5). Comparison to a molecular weight marker (at left) indicates a band of ~60 kDa corresponding to HR23A. The blot was incubated with a 1:500 dilution of the antibody at room temperature followed by detection using HRP conjugated Rb-a-Goat IgG and chemilumi-nescence reagent with a 30-min exposure time. Other detection systems will yield similar results.

 

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