Home Antibody All anti-RAD18 antibodies
Also for RAD18 (NM_020165)
|Recombinant fragment corresponding to a region within amino acids 1 and 259 of RAD18 (Uniprot ID#Q9NS91)|
|Human (Predicted: Bovine)
|WB, IHC, IF
||ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Bovine (80%)
|Homo sapiens RAD18 E3 ubiquitin protein ligase (RAD18)|
Entrez Gene 56852 Human
|The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens. [provided by RefSeq]|
|Druggable Genome |
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Sample (30 ug of whole cell lysate). A: Hep G2 . 7.5% SDS PAGE. TA308755 diluted at 1:1000.
Immunohistochemical analysis of paraffin-embedded Cal27 Xenograft, using RAD18(TA308755) antibody at 1:100 dilution.
RAD18 antibody [N1C1] detects RAD18 protein at nucleus by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: RAD18 protein stained by RAD18 antibody [N1C1] (TA308755) diluted at 1:500. Blue: Hoechst 3