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Anti-RABAC1 Antibody EPR1747Y
Also for RABAC1 (NM_006423)
|A synthetic peptide corresponding to residues near the C-terminus of human PRA1 was used as an immunogen.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:20000; IP: 1:30; FC: 1:100
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Is unsuitable for ICC or IHC-P.
|Homo sapiens Rab acceptor 1 (prenylated) (RABAC1)|
|PRA1; PRAF1; YIP3|
|PRA1 (prenylated Rab acceptor) is a general regulator of Rab proteins. It has been shown that PRA1 interacts with Rab proteins and with VAMP2. Therefore PRA1 is probably an important factor for membrane traffic, linking together the function of Rab proteins and SNAREs (1). Human cells contain more than 60 small G proteins of the Rab family, which are localized to the surfaces of distinct membrane compartments and regulate transport vesicle formation, motility, docking and fusion. Prenylated Rabs also occur in the cytosol bound to GDI (guanine nucleotide dissociation inhibitor), which binds to Rabs in their inactive state (2). |
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Western blot - PRA1 antibody [EPR1747Y] - Carboxyterminal end; Anti-PRA1 antibody [EPR1747Y] - Carboxyterminal end at 1/2000 dilution + 293 cell lysate at 10 µg.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 21 kDa.Observed band size : 21 kDa.