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Anti-RAB4A Antibody EPR3043
Also for RAB4A (NM_004578)
|A synthetic peptide corresponding to residues near the C-terminus of human Rab4 was used as an immunogen.|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000; IP: 1:10 - 1:100; ICC/IF: 1:500 - 1:1000
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Is unsuitable for Flow Cyt or IHC-P.
|Homo sapiens RAB4A, member RAS oncogene family (RAB4A), transcript variant 1|
|HRES-1; HRES-1/RAB4; HRES1; RAB4|
Entrez Gene 5867 Human
Entrez Gene 19341 Mouse
Entrez Gene 25532 Rat
|Rab proteins constitute a family of GTP-binding proteins that are located in distinct intracellular compartments and play a role in the regulation of vesicular trafficking (1). Rab4 (along with Rab5 and Rab11) regulate sequential transport steps along the endocytic/recycling pathway, and occupy distinct membrane domains on early and recycling endosomes. It seems that divalent Rab effectors regulate protein sorting and recycling by connecting Rab domains on early endosomes (2).|
|Druggable Genome Endocytosis|
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Western blot - Rab4 antibody [EPR3043]; All lanes : Anti-Rab4 antibody [EPR3043] at 1/1000 dilution.Lane 1 : MCF7 cell lysate.Lane 2 : PC12 cell lysate.Lane 3 : Neuro 2a cell lysate.Lane 4 : 293T cell lysate.Lane 5 : SH SY5Y cell lysate.Lane 6 : Human fetal brain lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 24 kDa.
Immunocytochemistry/ Immunofluorescence - Rab4 antibody [EPR3043]; TA307280 at 1/500 dilution staining Rab4 in HeLa by Immunofluorescence.