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Home Antibody All anti-QPRT antibodies

Anti-QPRT TRUEMAB Antibody clone 4B4

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA501523
  • anti-QPRT mouse monoclonal antibody, clone 4B4
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC402307) , 20ug
100ul 325 In Stock
CF501523
  • Carrier-free (BSA/glycerol-free) QPRT mouse monoclonal antibody, clone 4B4
100ug $450 3-4 weeks
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WB(2)
FC(1)
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Also for QPRT (NM_014298)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human QPRT (NP_055113) produced in HEK293T cell.
Clone Nameclone 4B4 IsotypeIgG1
Species ReactivityHuman Concentration0.69 mg/ml
Guaranteed Application *WB, FC Suggested DilutionsWB 1:500~2000, FLOW 1:100
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens quinolinate phosphoribosyltransferase (QPRT)
Alternative NameHEL-S-90n; QPRTase
Database LinkNP_055113
FunctionThis gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. [provided by RefSeq]. COMPLETENESS: complete on the 3' end.
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY QPRT (RC202960, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-QPRT.
WB Image
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-QPRT monoclonal antibody.
FC Image
HEK293T cells transfected with either RC202960 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-QPRT antibody(TA501523), and then analyzed by flow cytometry.

 

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