Home Antibody All anti-ProSAPiP1 antibodies
Also for ProSAPiP1 (NM_014731)
|Prosapip1 antibody was raised against a 16 amino acid peptide from near the carboxy terminus of human Prosapip1.|
|Human, Mouse, Rat
||WB: 1 - 2 ug/ml
|PBS containing 0.02% sodium azide.|
|Affinity chromatography purified via peptide column (Protein A or G Sepharose)
|Homo sapiens leucine zipper, putative tumor suppressor family member 3 (LZTS3)|
|Prosapip1 is a binding partner of the postsynaptic density (PSD) protein ProSAP2/Shank3, a major scaffolding protein in excitatory brain synapses. Prosapip1 is thought to bind ProSAP2/Shank3 through ProSAP2/Shank3’s PDZ domain and link it in turn to the Spine-associated Rap-Gap (SPAR). Prosapip1 shares significant homology with another PSD protein, PSD-Zip70, with both coding for a Fez1 domain that can be found in a total of four related protein, forming a novel family of scaffolding molecules termed ‘Fezzins’. Recent studies show that Prosapip1 can be found in endocrine cells in which it is localized primarily in the hormone-storing compartment of these cells, suggesting that Prosapip1 may have other functions in non-neuronal cells.|
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Western blot analysis of Prosapip1 in SK-N-SH cell lysate with Prosapip1 antibody at 1 µg/ml.
Immunohistochemistry of Prosapip1 in rat brain tissue with Prosapip1 antibody at 2.5 ug/ml.