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Home Antibody All anti-ProSAPiP1 antibodies

Anti-ProSAPiP1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306841
  • Rabbit Polyclonal Prosapip1 Antibody
100ug $325 3-7 Days
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WB(1)
IHC(1)
IF(1)
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Also for ProSAPiP1 (NM_014731)
cDNA Clone shRNA/siRNA Primer Pair Protein Request Antibody

OriGene Data

ImmunogenProsapip1 antibody was raised against a 16 amino acid peptide from near the carboxy terminus of human Prosapip1.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 ug/ml, IHC: 2.5 ug/ml, IF: 20 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens leucine zipper, putative tumor suppressor family member 3 (LZTS3)
Alternative NamePROSAPIP1; RP5-1187M17.10
Database LinkNP_055546
FunctionProsapip1 is a binding partner of the postsynaptic density (PSD) protein ProSAP2/Shank3, a major scaffolding protein in excitatory brain synapses. Prosapip1 is thought to bind ProSAP2/Shank3 through ProSAP2/Shank3’s PDZ domain and link it in turn to the Spine-associated Rap-Gap (SPAR). Prosapip1 shares significant homology with another PSD protein, PSD-Zip70, with both coding for a Fez1 domain that can be found in a total of four related protein, forming a novel family of scaffolding molecules termed ‘Fezzins’. Recent studies show that Prosapip1 can be found in endocrine cells in which it is localized primarily in the hormone-storing compartment of these cells, suggesting that Prosapip1 may have other functions in non-neuronal cells.
Related Pathway

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WB Image
Western blot analysis of Prosapip1 in SK-N-SH cell lysate with Prosapip1 antibody at 1 µg/ml.
IHC Image
Immunohistochemistry of Prosapip1 in rat brain tissue with Prosapip1 antibody at 2.5 ug/ml.
IF Image
Immunofluorescence of Prosapip 1 in rat brain tissue with Prosapip 1 antibody at 20 ug/mL.

 

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