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Home Antibody All anti-PTX3 antibodies

Anti-PTX3 Antibody EPR6699

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310796
  • Rabbit Monoclonal antibody against PTX3
  • FREE positive control: HEK293T cell transient overexpression lysate (LC419080) , 20ug
100ul 325 3-7 Days
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WB(1)
FC(1)
Assay(1)
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Also for PTX3 (NM_002852)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human PTX3 was used as an immunogen.
Clone NameEPR6699 IsotypeTissue culture supernatant
Species ReactivityHuman, Mouse Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, ASSAY, FC Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; FC: 1:10 - 1:100
BufferDoes not react with Rat. Is unsuitable for ICC or IHC-P.
Purification pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Note Is unsuitable for ICC or IHC-P.

Reference Data

Target NameHomo sapiens pentraxin 3, long (PTX3)
Alternative NameTNFAIP5; TSG-14
Database LinkNP_002843
FunctionThe long pentraxin 3 PTX3 is a member of a complex superfamily of multifunctional proteins, produced by innate-immunity cells in response to proinflammatory signals and Toll-like receptor engagement (1). PTX3 is a prototypic soluble pattern recognition molecule (PRM), thus the recognition of a microbial component by PTX3 can amplify the inflammatory response. It plays a role in the regulation of complement-mediated immune responses (2). PTX3 seems to also have unique immunoregulatory functions such as modulating the phagocytic uptake of apoptotic cells by macrophages and dendritic cells (3). A mutation in PTX3 is associated with a severe defect in female fertility (1).
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-Pentraxin 3 antibody [EPR6699]; All lanes : Anti-Pentraxin 3 antibody [EPR6699] at 1/1000 dilution.Lane 1 : HL-60 treated with Dexamethasone lysate.Lane 2 : HL-60 lysate.Lane 3 : Human spleen lysate.Lane 4 : NIH/3T3 cell lysate.Lane 5 : HUVEC lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 42 kDa.Observed band size : 42 kDa.
Assay Image
Other-Anti-Pentraxin 3 antibody [EPR6699](TA310796); Equilibrium disassociation constant (KD)..
FC Image
Flow Cytometry - Anti-Pentraxin 3 antibody [EPR6699]; Flow cytometric analysis of permeabilized HUVEC cells using TA310796 at 1/10 dilution (red) or a rabbit IgG (negative) (green).

 

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