Home Antibody All anti-PTS antibodies
|Recombinant fragment corresponding to a region within amino acids 1 and 145 of PTS (Uniprot ID#Q03393)|
|Human (Predicted: Bovine)
|WB, IHC, IF
||ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Bovine (84%)
|Homo sapiens 6-pyruvoyltetrahydropterin synthase (PTS)|
Entrez Gene 5805 Human
|The enzyme encoded by this gene catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin, also known as BH(4), is an essential cofactor and regulator of various enzyme activities, including enzymes involved in serotonin biosynthesis and NO synthase activity. Mutations in this gene result in hyperphenylalaninemia. [provided by RefSeq]|
|Druggable Genome Folate biosynthesisMetabolic pathways|
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Sample (50 ug of whole cell lysate). A: mouse stomach. 15% SDS PAGE. TA308040 diluted at 1:1000.
Sample (30 ug of whole cell lysate). A: H1299. 15% SDS PAGE. TA308040 diluted at 1:1000.
Immunohistochemical analysis of paraffin-embedded Hepatoma, using PTS(TA308040) antibody at 1:500 dilution.
Immunofluorescence analysis of methanol-fixed HeLa, using PTS(TA308040) antibody at 1:100 dilution.