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Home Antibody All anti-PTPRE antibodies

Anti-PTPRE TRUEMAB Antibody Clone OTI5E8

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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SKU Description Amount Price Availability*  
TA501026 anti-PTPRE (PTP epsilon) mouse monoclonal antibody, clone OTI5E8 (formerly 5E8) 100ul $325 In Stock
LC401950 PTPRE HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF501026 Carrier-free (BSA/glycerol-free) PTPRE mouse monoclonal antibody, clone OTI5E8 (formerly 5E8) 100ug $450 3-4 weeks
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WB(1)
IHC(6)
IF(1)
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Also for PTPRE (NM_006504)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human PTPRE (NP_006495) produced in HEK293T cell.
Clone NameClone OTI5E8 IsotypeIgG1
Species ReactivityHuman Concentration0.5 mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB 1:1000, IHC 1:50, IF 1:100,
Predicted MW Explanation 80.6 kDa
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens protein tyrosine phosphatase, receptor type, E (PTPRE), transcript variant 1
Alternative NameHPTPE; PTPE; R-PTP-EPSILON
Database LinkNP_006495
Entrez Gene 5791 Human
FunctionThe protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two alternatively spliced transcript variants of this gene have been reported,one of which encodes a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region,and two tandem intracytoplasmic catalytic domains; Another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokines induced SATA signaling, as well as the activation of voltage-gated K+ channels.
Related PathwayTransmembranePhosphataseDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PTPRE (RC207950, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PTPRE.
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Immunohistochemical staining of paraffin-embedded breast tissue within the normal limits using anti-PTPRE mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA501026, Dilution 1:50)
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of colon tissue using anti-PTPRE mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA501026, Dilution 1:50)
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Immunohistochemical staining of paraffin-embedded Kidney tissue within the normal limits using anti-PTPRE mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA501026, Dilution 1:50)
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Immunohistochemical staining of paraffin-embedded Carcinoma of liver tissue using anti-PTPRE mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA501026, Dilution 1:50)
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Immunohistochemical staining of paraffin-embedded Carcinoma of thyroid tissue using anti-PTPRE mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA501026, Dilution 1:50)
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Immunohistochemical staining of paraffin-embedded prostate tissue within the normal limits using anti-PTPRE mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA501026, Dilution 1:50)
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Anti-PTPRE mouse monoclonal antibody (TA501026) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PTPRE(RC207950).
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