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Home Antibody All anti-PTPRE antibodies

Anti-PTPRE Antibody EPR6715

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310795
  • Rabbit Monoclonal antibody against PTPRE
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401950) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
FC(1)
Assay(1)
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Also for PTPRE (NM_006504)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human PTPRE was used as an immunogen
Clone NameEPR6715 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY, FC Suggested DilutionsWB: 1:1000 - 1:10000; FC: 1:10 - 1:100
Predicted MW Explanation 71, 75, 81 kDa
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for ICC/IF,IHC-P or IP.

Reference Data

Target NameHomo sapiens protein tyrosine phosphatase, receptor type, E (PTPRE), transcript variant 1
Alternative NameHPTPE; PTPE; R-PTP-EPSILON
Database LinkNP_006495
Entrez Gene 5791 Human
Entrez Gene 19267 Mouse
Entrez Gene 114767 Rat
FunctionPTPRE is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two isoforms have been reported, one of which is a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; Another one is a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar protein in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokines induced SATA signaling, as well as the activation of voltage-gated K+ channels (1).
Related PathwayTransmembranePhosphataseDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-PTP epsilon antibody [EPR6715]; All lanes : Anti-PTP epsilon antibody [EPR6715] at 1/1000 dilution.Lane 1 : HL60 cell lysate, treated with TPA.Lane 2 : HL60 cell lysate.Lane 3 : HeLa cell lysate.Lane 4 : C2C12 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 71, 75, 81 kDa.
Assay Image
Other-Anti-PTP epsilon antibody [EPR6715](TA310795); Equilibrium disassociation constant (KD)..
FC Image
Flow Cytometry - Anti-PTP epsilon antibody [EPR6715]; TA310795 at 1/10 dilution staining PTP epsilon in permeabilized HL60 cells by Flow cytometry (red) compared with a rabbit IgG negative control (green).

 

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