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TA326012 Rabbit Polyclonal CD45 (Ser1007) Antibody (Phospho-specific) 100ul 325
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Also for PTPRC (NM_002838)
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OriGene Data

ImmunogenThe antiserum was produced against A synthesized peptide derived from human CD45 around the phosphorylation site of Serine 1007
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1:500-1:2000; IF/ICC: 1:100-1:500
Predicted MW Explanation 150kDa
BufferRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.

Reference Data

Target NameHomo sapiens protein tyrosine phosphatase, receptor type, C (PTPRC), transcript variant 1
Alternative NameB220; CD45; CD45R; GP180; L-CA; LCA; LY5; T200
Database LinkNP_002829
Entrez Gene 5788 Human
Entrez Gene 19264 Mouse
Entrez Gene 24699 Rat
FunctionThe protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation.
Related PathwayES Cell Differentiation/IPSTransmembranePhosphataseDruggable Genome Cell adhesion molecules (CAMs)T cell receptor signaling pathwayFc gamma R-mediated phagocytosisPrimary immunodeficiency

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of CD45 phosphorylation expression in TNF treated HeLa whole cell lysates,The lane on the left is treated with the antigen-specific peptide.


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