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Home Antibody All anti-PTPN2 antibodies

Anti-PTPN2 Antibody EPR6712

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310794
  • Rabbit Monoclonal antibody against PTPN2
100ul 325 3-7 Days
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WB(1)
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Also for PTPN2 (NM_080423)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human PTPN2 was used as an immunogen.
Clone NameEPR6712 IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC/IF or IHC-P.

Reference Data

Target NameHomo sapiens protein tyrosine phosphatase, non-receptor type 2 (PTPN2), transcript variant 3
Alternative NamePTN2; PTPT; TC-PTP; TCELLPTP; TCPTP
Database LinkNP_536348
FunctionPTPN2 is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of PTPN2, which suggested its roles in growth factor mediated cell signaling (1).
Related Pathway

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WB Image
Western blot - Anti-TCPTP antibody [EPR6712]; All lanes : Anti-TCPTP antibody [EPR6712] at 1/1000 dilution.Lane 1 : HL60 cell lysate.Lane 2 : NIH 3T3 cell lysate.Lane 3 : Mouse placenta lysate.Lane 4 : Mouse thymus lysate.Lane 5 : MOLT4 cell lysate.Lane 6 : HepG2 cell lysate.Lysates/proteins at 10 µg per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 48 kDa.Observed band size : 45-48 kDa .

 

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