Home Antibody All anti-PTK6 antibodies
Also for PTK6 (NM_005975)
|Synthetic peptide corresponding to residues surrounding amino acids 508 of human Brk|
|Human, mouse, rat
||WB: 0.5-4 ug/ml
|100 µg (0.5 mg/ml) affinity purified rabbit anti-Brk polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.|
|Affinity purified (Protein A or G Sepharose)
|Homo sapiens protein tyrosine kinase 6 (PTK6), transcript variant 1|
|Breast tumor kinase, Brk (also known as PTK6), is a member of intracellular tyrosine kinase family that is thought to be related to Src family of tumor related kinases. Brk is expressed in breast carcinomas but not in normal breast tissue. The presence of Brk in the nucleus appears to be linked to suppression of tumor progression and has been shown to undergo autophosphorylation.|
EGFR1 Signaling Pathway
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Western blot analysis of Brk in lysates from Jurkat cells (Lane 1,2), 3T3 cells (Lane 3) and rat kidney (Lane 4).