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Anti-PTEN PHOSPHO Antibody EP2138Y
Also for PTEN (NM_000314)
|A synthetic peptide corresponding to residues near serine 380 of human PTEN protein.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
||ICC: 1:100 - 250, IHC: 1:100 - 250, WB: 1:500 - 2000,
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant (Protein A or G Sepharose)
|Homo sapiens phosphatase and tensin homolog (PTEN)|
|10q23del; BZS; CWS1; DEC; GLM2; MHAM; MMAC1; PTEN1; TEP1|
|PTEN is a protein tyrosine phosphatase that acts as a tumor suppressor, as a lipid phosphatase that dephosphorylates the D3 position of phosphatidylinositol 3,4,5-trisphosphate and as an antagonist of the PI3k |
Senescence and Autophagy
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Western blot - PTEN (phospho S380) antibody [EP2138Y]; All lanes : Anti-PTEN (phospho S380) antibody [EP2138Y] at 1/2000 dilution.Lane 1 : NIH3T3 cell lysate.Lane 2 : NIH3T3 cell lysate treated with AP.Lysates/proteins at 10 µg per lane.Secondary.Goat anti-rabbit-HRP at 1/1000 dilution.Predicted band size : 47 kDa.Observed band size : 47 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - PTEN (phospho S380) antibody [EP2138Y]; ab76431, at a 1/100 dilution, staining PTEN in human uterine adenocarcinoma tissue by Immunohistochemistry.