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Home Antibody All anti-PSMF1 antibodies

Anti-PSMF1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA302572
  • Goat Polyclonal Antibody against PI31 / PSMF1 (Isoform 1)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC402038) , 20ug
100ug 325 In Stock
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WB(1)
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Also for PSMF1 (NM_006814)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenPeptide with sequence C-DHLPPPGYDDMYL, from the C Terminus of the protein sequence according to NP_006805.1; NP_848693.1.
Clone Name IsotypeGoat IgG
Species ReactivityHuman, Mouse, Rat, Dog Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB Suggested DilutionsELISA: 1/32000. WB: 0.5-2µg/ml.
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Reference Data

Target NameHomo sapiens proteasome (prosome, macropain) inhibitor subunit 1 (PI31) (PSMF1), transcript variant 1
Alternative NamePI31
Database LinkNP_006805
FunctionThe 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a protein that inhibits the activation of the proteasome by the 11S and 19S regulators. Alternative transcript variants have been identified for this gene. [provided by RefSeq].
Related Pathway
Cell cycle

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WB Image
TA302572 staining (1µg/ml) of Human Kidney lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

 

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