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Home Antibody All anti-PSMC3 antibodies

Anti-PSMC3 TRUEMAB Antibody Clone OTI7D1

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA500930 anti-PSMC3 mouse monoclonal antibody, clone OTI7D1 (formerly 7D1) 100ul $325 In Stock
LC400992 PSMC3 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF500930 Carrier-free (BSA/glycerol-free) PSMC3 mouse monoclonal antibody, clone OTI7D1 (formerly 7D1) 100ug $450 3-4 weeks

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

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WB(1)
IHC(1)
IF(1)
FC(1)
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Also for PSMC3 (NM_002804)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human PSMC3(NP_002795) produced in HEK293T cell.
Clone NameClone OTI7D1 IsotypeIgG2b
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IHC, IF, FC Suggested DilutionsWB 1:2000, IHC 1:50, IF 1:100, Flow 1:100
Predicted MW Explanation 49.2 kDa
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens proteasome (prosome, macropain) 26S subunit, ATPase, 3 (PSMC3)
Alternative NameTBP1
Database LinkNP_002795
Entrez Gene 5702 Human
FunctionThe 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits.Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases that have chaperone-like activity. This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. A pseudogene has been identified on chromosome 9.
Related PathwayTranscription FactorsDruggable Genome Proteasome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PSMC3 (RC201790, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PSMC3.
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Immunohistochemical staining of paraffin-embedded Kidney tissue within the normal limits using anti-PSMC3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500930, Dilution 1:50)
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Anti-PSMC3 mouse monoclonal antibody (TA500930) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PSMC3(RC201790).
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HEK293T cells transfected with either pCMV6-ENTRY PSMC3(RC201790)(Red) or empty vector control plasmid(Blue) were immunostained with anti-PSMC3 mouse monoclonal(TA500930), and then analyzed by flow cytometry.
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