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Home All anti-PSMA7 antibodies

Anti-PSMA7 Antibody

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SKU Description Amount Price Availability*  
TA308945
  • Rabbit Polyclonal antibody to Proteasome 20S alpha 7 (proteasome (prosome, macropain) subunit, alpha type, 7)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400987) , 20ug
100ul $325 3-7 Days
TA802519S
  • Purified GAPDH mouse monoclonal antibody (Loading control), clone 2D9
30ul
$100
$50*
In Stock
Add to Shopping Cart
* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
WB(2)
IHC(1)
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Also for PSMA7 (NM_002792)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenRecombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 175 of proteasome alpha 7
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration0.86mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB:1:500-1:3000; IHC:1:100;
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography. (Protein A or G Sepharose)

Reference Data

Target NameHomo sapiens proteasome (prosome, macropain) subunit, alpha type, 7 (PSMA7)
Alternative NameC6; HSPC; RC6-1; XAPC7
Database LinkNP_002783
FunctionThe proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. This particular subunit has been shown to interact specifically with the hepatitis B virus X protein, a protein critical to viral replication. In addition, this subunit is involved in regulating hepatitis virus C internal ribosome entry site (IRES) activity, an activity essential for viral replication. This core alpha subunit is also involved in regulating the hypoxia-inducible factor-1alpha, a transcription factor important for cellular responses to oxygen tension. Multiple isoforms of this subunit arising from alternative splicing may exist but alternative transcripts for only two isoforms have been defined. A pseudogene has been identified on chromosome 9. [provided by RefSeq]
Related Pathway
Cell cycle

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WB Image
A: A431 B: H1299 (anti-PSMA7 antibody diluted at 1:1000)
WB Image
A: mouse brain (anti-PSMA7 antibody diluted at 1:1000)
IHC Image
Immunohistochemical analysis of paraffin-embedded DLD-1 xenograft, using proteasome alpha 7(anti-PSMA7 antibody) antibody at 1:100 dilution.

 

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