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UltraMAB

PSMA6 UltraMAB Antibody, Clone UMAB102

UltraMAB™ Antibodies - Validated with 10K Protein Chip

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Specifications Citations Customer Reviews Product Documents
SKU Description Datasheet Price Availability*  
UM800032
  • PSMA6 mouse monoclonal antibody,clone UMAB102, 100 ul
$468 In Stock Add to Shopping Cart
UM870032
  • PSMA6 mouse monoclonal antibody,clone UMAB102, 30 ul
$120 In Stock Add to Shopping Cart
WB(2)
Data Img
IHC(5)
Data Img
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OriGene Data

ImmunogenFull length human recombinant protein of human PSMA6 (NP_002782) produced in E.coli.
Clone NameClone UMAB102 IsotypeIgG1
Species ReactivityHuman, Mouse, Rat, Monkey, Dog Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsIHC 1:100, IF 1:100
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens proteasome (prosome, macropain) subunit, alpha type, 6 (PSMA6), transcript variant 1
Alternative NameIOTA; p27K; PROS27
Database LinkNP_002782
FunctionThe proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. A pseudogene has been identified on the Y chromosome. [provided by RefSeq, Jul 2008].
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

Western blot of human tissue lysates (15ug) from 10 different tissues (1: Testis, 2: Omentum, 3: Uterus, 4: Breast, 5: Brain, 6: Liver, 7: Ovary, 8: Thyroid, 9: Colon, 10: Spleen ). Diluation: 1:500.
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Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-PSMA6 monoclonal antibody (Clone UMAB102).
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Immunohistochemical staining of 2 cases of paraffin-embedded human placenta using anti-PSMA6 clone UMAB102 mouse monoclonal antibody (UM800032) at 1:200 with Polink2 Broad HRP DAB detection kit; heat-induced epitope retrieval with GBI Citrate pH6.0 HIER buffer using pressure chamber for 3 minutes at 110C. Staining is nuclear, cytoplasmic, and membraneous in trophoblasts cells of the placenta.
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Immunohistochemical staining of 3 cases of paraffin-embedded human lung using anti-PSMA6 clone UMAB102 mouse monoclonal antibody (UM800032) at 1:200 with Polink2 Broad HRP DAB detection kit; heat-induced epitope retrieval with GBI Citrate pH6.0 HIER buffer using pressure chamber for 3 minutes at 110C. Most of the staining is nuclear in positive cells of the lung.
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Immunohistochemical staining of 3 cases of paraffin-embedded human endometrial carcinoma using anti-PSMA6 clone UMAB102 mouse monoclonal antibody (UM800032) at 1:200 with Polink2 Broad HRP DAB detection kit; heat-induced epitope retrieval with GBI Citrate pH6.0 HIER buffer using pressure chamber for 3 minutes at 110C. Cytoplasmic, membraneous and nuclear staining is seen in all 3 case of tumor cells.
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-PSMA6 mouse monoclonal antibody. (UM800032; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-PSMA6 mouse monoclonal antibody. (UM800032; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
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