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PSMA6 UltraMAB Antibody, Clone UMAB102
UltraMAB Antibodies - Validated with 10K Protein Chip
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Also for PSMA6 (NM_002791)
|Homo sapiens proteasome (prosome, macropain) subunit, alpha type, 6 (PSMA6), transcript variant 1|
|IOTA; p27K; PROS27|
|Full length human recombinant protein of human PSMA6 (NP_002782) produced in E.coli.|
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Human, Mouse, Rat, Monkey, Dog
||0.5~1.0 mg/ml (Lot Dependent)
|Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)
|WB, IHC, IF
||IHC 1:100, IF 1:100
|The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. A pseudogene has been identified on the Y chromosome. [provided by RefSeq, Jul 2008]. |
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Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-PSMA6 monoclonal antibody (Clone UMAB102).
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-PSMA6 mouse monoclonal antibody. (UM800032; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-PSMA6 mouse monoclonal antibody. (UM800032; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
Immunofluorescent staining of A549 cells using PSMA6 mouse monoclonal antibody (UM800032, green). Actin filaments were labeled with TRITC-phalloidin (red), and nuclear with DAPI (blue). The three-color overlay image is located at the bottom-right corner.