Anti-PSMA6 Antibody,

Also for PSMA6 (NM_002791)

OriGene Data

Immunogen	Recombinant protein fragment contain a sequence corresponding to a region within amino acids 57 and 244 of 20S Proteasome alpha6
Clone Name		Isotype	IgG
Species Reactivity	Human, Mouse	Concentration	1mg/ml
Guaranteed Application *	WB, IHC, IF	Suggested Dilutions	WB:1:500-1:3000; IHC:1:100; IF:1:100-1:500;
Buffer	0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification	Purified by antigen-affinity chromatography. (Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens proteasome (prosome, macropain) subunit, alpha type, 6 (PSMA6)
Alternative Name	IOTA; p27K; PROS27
Database Link	NP_002782
Function	The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. A pseudogene has been identified on the Y chromosome. [provided by RefSeq]
Related Pathway	Cell cycle

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WB Image

A: 293T B: A431 C: H1299 D: Hela (anti-PSMA6 antibody diluted at 1:1000)

WB Image

A: mouse brain (anti-PSMA6 antibody diluted at 1:1000)

IHC Image

Immunohistochemical analysis of paraffin-embedded H1299 xenograft , using 20S Proteasome alpha6 (anti-PSMA6 antibody) antibody at 1:100 dilution.

IF Image

Immunofluorescence analysis of paraformaldehyde-fixed A431, using 20S Proteasome alpha6 (anti-PSMA6 antibody) antibody at 1:200 dilution.

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

HRP
Biotin
PE
FITC
DyLight® 488
DyLight® 550
DyLight® 594
DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Anti-PSMA6 Antibody

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

OriGene Data

Reference Data